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News & announcements

Product launches, research breakthroughs, and company milestones from the Vecentra team.

Research
October 23, 2026 9 min

The Itraconazole Mystery: Gnosis points to SMO

A widely used antifungal with unexpected anticancer activity and more than fifteen years of mechanistic debate. In a structural comparison against SMO and VDAC1, Vecentra favours SMO as the clearer predicted interaction, and turns a long question into a focused next experiment.

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Research
October 20, 2026 7 min

Would it have worked? Testing our models against the drugs that failed

Potency does not separate the oncology drugs that reached patients from the ones that failed. Across 22 compounds and 8 cancer targets, target engagement and cohort biology do. A retrospective research note, with the limits stated plainly.

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Product
March 18, 2026 8 min

Introducing Gnosis: an integrated AI system for small-molecule drug design

Gnosis unifies molecular generation and multi-property evaluation (target engagement, selectivity, safety, omics, and ADMET) into a single decision system, with a growing focus on RNA-targeting and induced-proximity chemistry to reach historically undruggable targets.

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Research
March 2, 2026 7 min

Research note: predicting cancer cytotoxicity from multi-omics signals

The most valuable signal in early cancer drug design is not raw potency, it is selectivity. A note on why predicting cytotoxicity well means predicting biology, and how multi-omics nudges models toward mechanism instead of memorisation.

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Company
February 14, 2026 4 min

Building Vecentra, and where the work actually goes

An early company note on who is building Gnosis, what the resources are for, and why we are not going to pretend a round announcement is the interesting part.

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Announcements
January 9, 2026 4 min

How a team actually uses Gnosis

The product is not an endpoint. It is a decision about which molecules to make next, delivered as a Candidate Intelligence Codex rather than an unattended API.

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